Priogen’s IP portfolio spans a range of innovations across methodologies, reagents, and hardware platforms, including Nano-QuIC™ for highly sensitive blood-based detection of Parkinson’s disease biomarkers and Micro-QuIC™ for ultra-rapid seed amplification with results in under four hours.
Silica nanoparticle seed amplification assay that overcomes blood inhibitors, with proven detection of Parkinson's disease biomarkers. Peer-reviewed publications: Christenson et al. 2023, Christenson et al. 2024, Jeong et al. 2026
Only hardware customized for seed amplification assay. Detects Parkinson's biomarkers in real-time on a stand-alone device. High -throughput testing with onboard data analysis.
Portable seed amplification assay providing results in less than 4 hours. Leverages microfluidics and sound-driven mixing to detect protein misfolding. Peer-reviewed publication: Lee et al. 2024
Gold nanoparticle seeded amplification assay that distinguishes positive and negative samples using light-absorbance. MN-QuIC™ uses field-deployable hardware with results in less than 24 hours. Peer-reviewed publication: Christenson et al. 2022
Sensitive biomarker recovery from a wide variety of surfaces. Usage examples include: confirmatory prion decontamination of surgical instruments and operating surfaces in hospitals and clinics, prion tracking in meat processing facilities, and saliva-based sentinel monitoring in animals. Peer-reviewed publications: Yuan et al. 2022, Simmons et al. 2024, Milstein et al. 2025, Huang et al. 2025