Priogen's IP portfolio includes Nano-QuIC™ for blood-based Parkinson's disease biomarker detection and Micro-QuIC™ for rapid seed amplification in under 4 hours
Silica nanoparticle seed amplification assay that overcomes blood inhibitors, with proven detection of Parkinson's disease biomarkers. Peer-reviewed publications: Christenson et al. 2023 Christenson et al. 2024
White dots in this image are sound-based amplified prions in a microfluidic chamber. Using this approach, the prion disease (CWD) was detected in less than 4 hours.
Portable seeded amplification assay providing results in less than 4 hours. Leverages microfluidics and sound-driven mixing to detect protein misfolding. Peer-reviewed publication: Lee et al. 2024
Gold nanoparticle seeded amplification assay that distinguishes positive and negative samples using light-absorbance. MN-QuIC™ uses field-deployable hardware with results in less than 24 hours. Peer-reviewed publication: Christenson et al. 2022
Powerful prion recovery from a wide variety of surfaces. Usage examples range from prion tracking in meat processing facilities and saliva-based sentinel monitoring in animals to confirmatory prion decontamination of surgical instruments and operating surfaces in hospitals and clinics. Peer-reviewed publications: Yuan et al. 2022, Simmons et al. 2024, Milstein et al. 2025, Huang et al. 2025